<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:01a043c1-31b0-76ec-9d69-58b33557a0fb,g:b1ba6558-fe47-4343-ab68-1df6aa626a4b-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:arcroleRef arcroleURI="https://xbrl.org/2023/arcrole/summation-item" xlink:type="simple" xlink:href="https://www.xbrl.org/2023/calculation-1.1.xsd#summation-item"/>
  <link:roleRef roleURI="http://www.abbott.com/role/CondensedConsolidatedStatementofEarnings" xlink:type="simple" xlink:href="abt-20260930.xsd#CondensedConsolidatedStatementofEarnings"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/CondensedConsolidatedStatementofEarnings" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_01a043c1-33c6-74de-b46c-67fe21adaeb1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_01a043c1-33c6-7bef-9fee-ad83df059bb4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_01a043c1-33c6-74de-b46c-67fe21adaeb1" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_01a043c1-33c6-7bef-9fee-ad83df059bb4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_01a043c1-33c6-7851-9dc3-13c509a5a16e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_01a043c1-33c6-74de-b46c-67fe21adaeb1" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_01a043c1-33c6-7851-9dc3-13c509a5a16e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c6-7b73-9428-d2025a4eb301" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_01a043c1-33c6-7b2b-8a19-0ced6c05e2a0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c6-7b73-9428-d2025a4eb301" xlink:to="loc_us-gaap_OperatingIncomeLoss_01a043c1-33c6-7b2b-8a19-0ced6c05e2a0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseNonoperating_01a043c1-33c6-7a57-ae0a-b183af42eb20" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestExpenseNonoperating"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c6-7b73-9428-d2025a4eb301" xlink:to="loc_us-gaap_InterestExpenseNonoperating_01a043c1-33c6-7a57-ae0a-b183af42eb20" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeInterest_01a043c1-33c6-74fb-aa1d-2004a34578b3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentIncomeInterest"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c6-7b73-9428-d2025a4eb301" xlink:to="loc_us-gaap_InvestmentIncomeInterest_01a043c1-33c6-74fb-aa1d-2004a34578b3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_01a043c1-33c6-7d66-bb76-63b778dec627" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c6-7b73-9428-d2025a4eb301" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_01a043c1-33c6-7d66-bb76-63b778dec627" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_01a043c1-33c6-7121-b71a-a898d15b6704" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c6-7b73-9428-d2025a4eb301" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_01a043c1-33c6-7121-b71a-a898d15b6704" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_01a043c1-33c6-7f67-99f8-b0f5876400c8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostsAndExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_01a043c1-33c6-73df-9bf7-bd26cdcb90bf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_01a043c1-33c6-7f67-99f8-b0f5876400c8" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_01a043c1-33c6-73df-9bf7-bd26cdcb90bf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_01a043c1-33c6-78db-b87b-61cfd2b320f1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_01a043c1-33c6-7f67-99f8-b0f5876400c8" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_01a043c1-33c6-78db-b87b-61cfd2b320f1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_01a043c1-33c6-71c1-b4b0-b22f3a35de63" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_01a043c1-33c6-7f67-99f8-b0f5876400c8" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_01a043c1-33c6-71c1-b4b0-b22f3a35de63" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_01a043c1-33c6-7410-9347-98e498ad0dc0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_01a043c1-33c6-7f67-99f8-b0f5876400c8" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_01a043c1-33c6-7410-9347-98e498ad0dc0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_01a043c1-33c6-7b95-8ffb-952ef8276215" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a043c1-33c6-7cbf-a4eb-1d22c8cf65d4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_01a043c1-33c6-7b95-8ffb-952ef8276215" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a043c1-33c6-7cbf-a4eb-1d22c8cf65d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_01a043c1-33c6-73f3-851e-605084bc6c60" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostsAndExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_01a043c1-33c6-7b95-8ffb-952ef8276215" xlink:to="loc_us-gaap_CostsAndExpenses_01a043c1-33c6-73f3-851e-605084bc6c60" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_01a043c1-33c6-72c2-af3e-bf10c6aa654a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c6-7760-9eb6-4dae02d8a830" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_01a043c1-33c6-72c2-af3e-bf10c6aa654a" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c6-7760-9eb6-4dae02d8a830" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_01a043c1-33c6-7d85-9381-bff4e237845c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_01a043c1-33c6-72c2-af3e-bf10c6aa654a" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_01a043c1-33c6-7d85-9381-bff4e237845c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/CondensedConsolidatedStatementofComprehensiveIncome" xlink:type="simple" xlink:href="abt-20260930.xsd#CondensedConsolidatedStatementofComprehensiveIncome"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/CondensedConsolidatedStatementofComprehensiveIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_01a043c1-33c6-7027-a334-33ef06279022" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_01a043c1-33c6-75e8-9a48-b9feead52d5f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_01a043c1-33c6-7027-a334-33ef06279022" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_01a043c1-33c6-75e8-9a48-b9feead52d5f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_01a043c1-33c6-7a0b-b665-d68d4dc072fd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_01a043c1-33c6-7027-a334-33ef06279022" xlink:to="loc_us-gaap_NetIncomeLoss_01a043c1-33c6-7a0b-b665-d68d4dc072fd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_01a043c1-33c6-792b-a0fc-10f3c8a0dc27" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_01a043c1-33c6-7cb9-ae19-5c271282b102" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_01a043c1-33c6-792b-a0fc-10f3c8a0dc27" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_01a043c1-33c6-7cb9-ae19-5c271282b102" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_01a043c1-33c6-783e-abd1-d007ce219bc8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_01a043c1-33c6-792b-a0fc-10f3c8a0dc27" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_01a043c1-33c6-783e-abd1-d007ce219bc8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_01a043c1-33c6-7d95-b2f5-4b1d39f6e10d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_01a043c1-33c6-792b-a0fc-10f3c8a0dc27" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_01a043c1-33c6-7d95-b2f5-4b1d39f6e10d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7a0a-96e6-0690b0ebf19c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax_01a043c1-33c6-78cb-9373-ec76b7aae2e7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7a0a-96e6-0690b0ebf19c" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax_01a043c1-33c6-78cb-9373-ec76b7aae2e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_01a043c1-33c6-7bc3-be31-8364cd5bb38f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7a0a-96e6-0690b0ebf19c" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_01a043c1-33c6-7bc3-be31-8364cd5bb38f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax_01a043c1-33c6-76d1-87cc-6cc846cb26c9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7a0a-96e6-0690b0ebf19c" xlink:to="loc_us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax_01a043c1-33c6-76d1-87cc-6cc846cb26c9" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/CondensedConsolidatedBalanceSheet" xlink:type="simple" xlink:href="abt-20260930.xsd#CondensedConsolidatedBalanceSheet"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/CondensedConsolidatedBalanceSheet" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_01a043c1-33c6-76da-832e-ad9e2c9dbd99" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_01a043c1-33c6-73cb-a270-569d68669a2a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_01a043c1-33c6-76da-832e-ad9e2c9dbd99" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_01a043c1-33c6-73cb-a270-569d68669a2a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_01a043c1-33c6-7e75-a9aa-5381c780276b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_01a043c1-33c6-76da-832e-ad9e2c9dbd99" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_01a043c1-33c6-7e75-a9aa-5381c780276b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_01a043c1-33c6-7e0a-ac9e-84a60c1b7007" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_01a043c1-33c6-7424-87c1-6dcb149aee7f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_01a043c1-33c6-7e0a-ac9e-84a60c1b7007" xlink:to="loc_us-gaap_StockholdersEquity_01a043c1-33c6-7424-87c1-6dcb149aee7f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MinorityInterest_01a043c1-33c6-75ac-b42a-321fcdb88e38" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_MinorityInterest"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_01a043c1-33c6-7e0a-ac9e-84a60c1b7007" xlink:to="loc_us-gaap_MinorityInterest_01a043c1-33c6-75ac-b42a-321fcdb88e38" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_01a043c1-33c6-7d88-a65d-0b4bc227ad80" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-7500-988a-e15ab567c18e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_01a043c1-33c6-7d88-a65d-0b4bc227ad80" xlink:to="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-7500-988a-e15ab567c18e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_01a043c1-33c6-7a25-b861-0bef7d0662d9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_01a043c1-33c6-7d88-a65d-0b4bc227ad80" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_01a043c1-33c6-7a25-b861-0bef7d0662d9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_01a043c1-33c6-7ad9-ac71-553f2d803325" xlink:href="abt-20260930.xsd#abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_01a043c1-33c6-7d88-a65d-0b4bc227ad80" xlink:to="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_01a043c1-33c6-7ad9-ac71-553f2d803325" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_01a043c1-33c6-7952-8904-df69639b5776" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_01a043c1-33c6-7d88-a65d-0b4bc227ad80" xlink:to="loc_us-gaap_CommitmentsAndContingencies_01a043c1-33c6-7952-8904-df69639b5776" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_01a043c1-33c6-70e0-9d82-bd58b733736d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_01a043c1-33c6-7d88-a65d-0b4bc227ad80" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_01a043c1-33c6-70e0-9d82-bd58b733736d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-77c3-82d4-41e87f37651c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableTradeCurrent_01a043c1-33c6-7e48-b527-710faf8bccd9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsPayableTradeCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-77c3-82d4-41e87f37651c" xlink:to="loc_us-gaap_AccountsPayableTradeCurrent_01a043c1-33c6-7e48-b527-710faf8bccd9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_01a043c1-33c6-7e17-ab45-4be8738b42f9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-77c3-82d4-41e87f37651c" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_01a043c1-33c6-7e17-ab45-4be8738b42f9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_01a043c1-33c6-706c-8c12-7f75b892468d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-77c3-82d4-41e87f37651c" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_01a043c1-33c6-706c-8c12-7f75b892468d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsPayableCurrent_01a043c1-33c6-75ef-894d-c79730d848f6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DividendsPayableCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-77c3-82d4-41e87f37651c" xlink:to="loc_us-gaap_DividendsPayableCurrent_01a043c1-33c6-75ef-894d-c79730d848f6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedIncomeTaxesCurrent_01a043c1-33c6-7d9e-9619-51638cb3c45e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedIncomeTaxesCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-77c3-82d4-41e87f37651c" xlink:to="loc_us-gaap_AccruedIncomeTaxesCurrent_01a043c1-33c6-7d9e-9619-51638cb3c45e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_01a043c1-33c6-7174-8de2-d7865bf04f76" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_01a043c1-33c6-77c3-82d4-41e87f37651c" xlink:to="loc_us-gaap_LongTermDebtCurrent_01a043c1-33c6-7174-8de2-d7865bf04f76" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_01a043c1-33c6-7c55-8839-7b8314738efa" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_01a043c1-33c6-71d6-959e-f41fad30500e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PreferredStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_01a043c1-33c6-7c55-8839-7b8314738efa" xlink:to="loc_us-gaap_PreferredStockValue_01a043c1-33c6-71d6-959e-f41fad30500e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_01a043c1-33c6-7415-850a-809f133046c2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_01a043c1-33c6-7c55-8839-7b8314738efa" xlink:to="loc_us-gaap_CommonStockValue_01a043c1-33c6-7415-850a-809f133046c2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonValue_01a043c1-33c6-73f8-a72f-55f5f8cd08d5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TreasuryStockCommonValue"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_01a043c1-33c6-7c55-8839-7b8314738efa" xlink:to="loc_us-gaap_TreasuryStockCommonValue_01a043c1-33c6-73f8-a72f-55f5f8cd08d5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_01a043c1-33c6-7572-a8f3-9313cc3acb41" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_01a043c1-33c6-7c55-8839-7b8314738efa" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_01a043c1-33c6-7572-a8f3-9313cc3acb41" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7add-bdb2-166b5600fb6a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_01a043c1-33c6-7c55-8839-7b8314738efa" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7add-bdb2-166b5600fb6a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_01a043c1-33c6-7581-8fb3-17ae38edcd3e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_01a043c1-33c6-7f85-b5dc-c07e69bef281" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_01a043c1-33c6-7581-8fb3-17ae38edcd3e" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_01a043c1-33c6-7f85-b5dc-c07e69bef281" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermInvestments_01a043c1-33c6-7ab1-8ff4-7b3002da9c30" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShortTermInvestments"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_01a043c1-33c6-7581-8fb3-17ae38edcd3e" xlink:to="loc_us-gaap_ShortTermInvestments_01a043c1-33c6-7ab1-8ff4-7b3002da9c30" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_01a043c1-33c6-7783-9c38-860a1e796a2f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_01a043c1-33c6-7581-8fb3-17ae38edcd3e" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_01a043c1-33c6-7783-9c38-860a1e796a2f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_01a043c1-33c6-70ac-b157-f97082e481c5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_01a043c1-33c6-7581-8fb3-17ae38edcd3e" xlink:to="loc_us-gaap_InventoryNet_01a043c1-33c6-70ac-b157-f97082e481c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_PrepaidExpenseAndOtherReceivables_01a043c1-33c6-7255-80bf-a2ad758649f8" xlink:href="abt-20260930.xsd#abt_PrepaidExpenseAndOtherReceivables"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_01a043c1-33c6-7581-8fb3-17ae38edcd3e" xlink:to="loc_abt_PrepaidExpenseAndOtherReceivables_01a043c1-33c6-7255-80bf-a2ad758649f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_01a043c1-33c6-7f3a-83bd-74543b233a6d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_01a043c1-33c6-756f-8b05-b9ece8ab32e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_01a043c1-33c6-7f3a-83bd-74543b233a6d" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_01a043c1-33c6-756f-8b05-b9ece8ab32e2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_01a043c1-33c6-7f2f-a53a-58c9b7619149" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_01a043c1-33c6-7f3a-83bd-74543b233a6d" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_01a043c1-33c6-7f2f-a53a-58c9b7619149" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_01a043c1-33c6-7385-9cdf-803a3a61212f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryRawMaterialsNetOfReserves"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_01a043c1-33c6-7f3a-83bd-74543b233a6d" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_01a043c1-33c6-7385-9cdf-803a3a61212f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_01a043c1-33c6-774c-9411-9c1f00254804" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_01a043c1-33c6-7138-af98-ec3fd895c278" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_01a043c1-33c6-774c-9411-9c1f00254804" xlink:to="loc_us-gaap_AssetsCurrent_01a043c1-33c6-7138-af98-ec3fd895c278" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermInvestments_01a043c1-33c6-7358-a6aa-ccf7860d22b4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermInvestments"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_01a043c1-33c6-774c-9411-9c1f00254804" xlink:to="loc_us-gaap_LongTermInvestments_01a043c1-33c6-7358-a6aa-ccf7860d22b4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_01a043c1-33c6-7ddf-83e7-e461ee1513c6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_01a043c1-33c6-774c-9411-9c1f00254804" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_01a043c1-33c6-7ddf-83e7-e461ee1513c6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_01a043c1-33c6-7bb2-aa64-93c0c6ce4033" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_01a043c1-33c6-774c-9411-9c1f00254804" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_01a043c1-33c6-7bb2-aa64-93c0c6ce4033" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_01a043c1-33c6-7a60-99fa-f23ce07f898a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_01a043c1-33c6-774c-9411-9c1f00254804" xlink:to="loc_us-gaap_Goodwill_01a043c1-33c6-7a60-99fa-f23ce07f898a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndOtherAssetsNoncurrent_01a043c1-33c6-7de4-8fed-35e2c3a808e7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredIncomeTaxesAndOtherAssetsNoncurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_01a043c1-33c6-774c-9411-9c1f00254804" xlink:to="loc_us-gaap_DeferredIncomeTaxesAndOtherAssetsNoncurrent_01a043c1-33c6-7de4-8fed-35e2c3a808e7" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/CondensedConsolidatedStatementofCashFlows" xlink:type="simple" xlink:href="abt-20260930.xsd#CondensedConsolidatedStatementofCashFlows"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/CondensedConsolidatedStatementofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a043c1-33c6-7cff-84ea-79714489c771" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_01a043c1-33c6-788c-9af9-603234dc1a7f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a043c1-33c6-7cff-84ea-79714489c771" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_01a043c1-33c6-788c-9af9-603234dc1a7f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_PaymentsToAcquireBusinessesNetOfCashAcquiredAndResearchAndDevelopmentInProcess_01a043c1-33c6-735c-a5d2-6d0b98d705f5" xlink:href="abt-20260930.xsd#abt_PaymentsToAcquireBusinessesNetOfCashAcquiredAndResearchAndDevelopmentInProcess"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a043c1-33c6-7cff-84ea-79714489c771" xlink:to="loc_abt_PaymentsToAcquireBusinessesNetOfCashAcquiredAndResearchAndDevelopmentInProcess_01a043c1-33c6-735c-a5d2-6d0b98d705f5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromInvestments_01a043c1-33c6-72bf-9943-e217d5833904" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsForProceedsFromInvestments"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a043c1-33c6-7cff-84ea-79714489c771" xlink:to="loc_us-gaap_PaymentsForProceedsFromInvestments_01a043c1-33c6-72bf-9943-e217d5833904" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_01a043c1-33c6-75b2-bf17-b0c57bbd6535" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a043c1-33c6-7cff-84ea-79714489c771" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_01a043c1-33c6-75b2-bf17-b0c57bbd6535" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7867-84a9-f18e54121cc9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_01a043c1-33c6-794a-80eb-85d0e8c8af0d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7867-84a9-f18e54121cc9" xlink:to="loc_us-gaap_NetIncomeLoss_01a043c1-33c6-794a-80eb-85d0e8c8af0d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_01a043c1-33c6-7f14-b1e6-63339847a28b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Depreciation"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7867-84a9-f18e54121cc9" xlink:to="loc_us-gaap_Depreciation_01a043c1-33c6-7f14-b1e6-63339847a28b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_01a043c1-33c6-7740-bd6e-1072974de0c4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7867-84a9-f18e54121cc9" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_01a043c1-33c6-7740-bd6e-1072974de0c4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_01a043c1-33c6-7ea2-9291-57bcc6b1ab1d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7867-84a9-f18e54121cc9" xlink:to="loc_us-gaap_ShareBasedCompensation_01a043c1-33c6-7ea2-9291-57bcc6b1ab1d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_01a043c1-33c6-78f5-8547-dbc529c90489" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7867-84a9-f18e54121cc9" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_01a043c1-33c6-78f5-8547-dbc529c90489" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_01a043c1-33c6-7d08-8601-f188e29ab6f7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7867-84a9-f18e54121cc9" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_01a043c1-33c6-7d08-8601-f188e29ab6f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingCapitalNet_01a043c1-33c6-7de2-a635-adc75167321d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInOtherOperatingCapitalNet"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7867-84a9-f18e54121cc9" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingCapitalNet_01a043c1-33c6-7de2-a635-adc75167321d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_01a043c1-33c6-7293-b6a9-262929260a34" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7171-bbaa-1e21a5c6438a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_01a043c1-33c6-7293-b6a9-262929260a34" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a043c1-33c6-7171-bbaa-1e21a5c6438a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a043c1-33c6-781d-a1e6-8d995a7a4f0d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_01a043c1-33c6-7293-b6a9-262929260a34" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a043c1-33c6-781d-a1e6-8d995a7a4f0d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7737-a24e-995c8885b0bc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_01a043c1-33c6-7293-b6a9-262929260a34" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7737-a24e-995c8885b0bc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_01a043c1-33c6-7229-830d-4f34ebab86ca" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_01a043c1-33c6-7293-b6a9-262929260a34" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_01a043c1-33c6-7229-830d-4f34ebab86ca" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7a3a-a6ec-981fc67e4680" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebt_01a043c1-33c6-713b-8d29-0840fbe49214" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromRepaymentsOfShortTermDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7a3a-a6ec-981fc67e4680" xlink:to="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebt_01a043c1-33c6-713b-8d29-0840fbe49214" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_01a043c1-33c6-7399-b0c9-2ff947e286d4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7a3a-a6ec-981fc67e4680" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_01a043c1-33c6-7399-b0c9-2ff947e286d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_01a043c1-33c6-7079-8057-2a96457f44b7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7a3a-a6ec-981fc67e4680" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_01a043c1-33c6-7079-8057-2a96457f44b7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_01a043c1-33c6-751f-a659-69624466ff3e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7a3a-a6ec-981fc67e4680" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_01a043c1-33c6-751f-a659-69624466ff3e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_01a043c1-33c6-7e04-b1e7-8ced68252591" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7a3a-a6ec-981fc67e4680" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_01a043c1-33c6-7e04-b1e7-8ced68252591" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock_01a043c1-33c6-783e-b0a0-9a12a1b21d74" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7a3a-a6ec-981fc67e4680" xlink:to="loc_us-gaap_PaymentsOfDividendsCommonStock_01a043c1-33c6-783e-b0a0-9a12a1b21d74" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_01a043c1-33c6-7ac7-a9e4-fc92fd97412a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a043c1-33c6-7a3a-a6ec-981fc67e4680" xlink:to="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_01a043c1-33c6-7ac7-a9e4-fc92fd97412a" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/ChangesInAccumulatedOtherComprehensiveIncomeLossScheduleofChangesinAccumulatedOtherComprehensiveIncomeLossNetofTaxDetails" xlink:type="simple" xlink:href="abt-20260930.xsd#ChangesInAccumulatedOtherComprehensiveIncomeLossScheduleofChangesinAccumulatedOtherComprehensiveIncomeLossNetofTaxDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/ChangesInAccumulatedOtherComprehensiveIncomeLossScheduleofChangesinAccumulatedOtherComprehensiveIncomeLossNetofTaxDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7661-a4fa-d0c2b60364e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_01a043c1-33c6-752b-ab20-0e0147a5ad7c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7661-a4fa-d0c2b60364e2" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_01a043c1-33c6-752b-ab20-0e0147a5ad7c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_01a043c1-33c6-7568-9076-81944a381b12" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_01a043c1-33c6-7661-a4fa-d0c2b60364e2" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_01a043c1-33c6-7568-9076-81944a381b12" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/BusinessAcquisitionScheduleofPreliminaryAllocationoftheFairValueDetails" xlink:type="simple" xlink:href="abt-20260930.xsd#BusinessAcquisitionScheduleofPreliminaryAllocationoftheFairValueDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/BusinessAcquisitionScheduleofPreliminaryAllocationoftheFairValueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_01a043c1-33c6-7005-b53a-d96c99b35a77" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_01a043c1-33c6-733b-b04a-66acb78f591f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_01a043c1-33c6-7005-b53a-d96c99b35a77" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_01a043c1-33c6-733b-b04a-66acb78f591f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_01a043c1-33c6-7de6-965a-f50653e5d5e9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_01a043c1-33c6-7005-b53a-d96c99b35a77" xlink:to="loc_us-gaap_Goodwill_01a043c1-33c6-7de6-965a-f50653e5d5e9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_BusinessCombinationRecognizedAssetAcquiredTangibleAssetNet_01a043c1-33c6-7edf-8dff-dadc81e409e6" xlink:href="abt-20260930.xsd#abt_BusinessCombinationRecognizedAssetAcquiredTangibleAssetNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_01a043c1-33c6-7005-b53a-d96c99b35a77" xlink:to="loc_abt_BusinessCombinationRecognizedAssetAcquiredTangibleAssetNet_01a043c1-33c6-7edf-8dff-dadc81e409e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_01a043c1-33c6-7ffb-8a15-4d436df66485" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_01a043c1-33c6-7005-b53a-d96c99b35a77" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_01a043c1-33c6-7ffb-8a15-4d436df66485" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDebtNet_01a043c1-33c6-7e8b-88a5-59a807ddb4f7" xlink:href="abt-20260930.xsd#abt_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDebtNet"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_01a043c1-33c6-7005-b53a-d96c99b35a77" xlink:to="loc_abt_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDebtNet_01a043c1-33c6-7e8b-88a5-59a807ddb4f7" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/FinancialInstrumentsDerivativesandFairValueMeasuresScheduleofBasesUsedtoMeasureAssetsandLiabilitiesatFairValueonaRecurringBasisDetails" xlink:type="simple" xlink:href="abt-20260930.xsd#FinancialInstrumentsDerivativesandFairValueMeasuresScheduleofBasesUsedtoMeasureAssetsandLiabilitiesatFairValueonaRecurringBasisDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/FinancialInstrumentsDerivativesandFairValueMeasuresScheduleofBasesUsedtoMeasureAssetsandLiabilitiesatFairValueonaRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_01a043c1-33c6-7bba-9864-f3454f2a2490" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_01a043c1-33c6-7fb5-ab84-6259fc3f1302" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_01a043c1-33c6-7bba-9864-f3454f2a2490" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_01a043c1-33c6-7fb5-ab84-6259fc3f1302" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyCashFlowHedgeAssetAtFairValue_01a043c1-33c6-7b18-8296-eaa83b7b69d8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ForeignCurrencyCashFlowHedgeAssetAtFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_01a043c1-33c6-7bba-9864-f3454f2a2490" xlink:to="loc_us-gaap_ForeignCurrencyCashFlowHedgeAssetAtFairValue_01a043c1-33c6-7b18-8296-eaa83b7b69d8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_01a043c1-33c6-7121-9640-2a5cbaf5ab7d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedge_01a043c1-33c6-7134-b018-b14cdb682eb4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgedLiabilityFairValueHedge"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_01a043c1-33c6-7121-9640-2a5cbaf5ab7d" xlink:to="loc_us-gaap_HedgedLiabilityFairValueHedge_01a043c1-33c6-7134-b018-b14cdb682eb4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateDerivativeLiabilitiesAtFairValue_01a043c1-33c6-730d-9360-26909c5622e8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestRateDerivativeLiabilitiesAtFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_01a043c1-33c6-7121-9640-2a5cbaf5ab7d" xlink:to="loc_us-gaap_InterestRateDerivativeLiabilitiesAtFairValue_01a043c1-33c6-730d-9360-26909c5622e8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue_01a043c1-33c6-7a8c-bed3-da9968fc5732" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_01a043c1-33c6-7121-9640-2a5cbaf5ab7d" xlink:to="loc_us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue_01a043c1-33c6-7a8c-bed3-da9968fc5732" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_01a043c1-33c6-7f8f-9788-9ea22c0efc31" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_01a043c1-33c6-7121-9640-2a5cbaf5ab7d" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_01a043c1-33c6-7f8f-9788-9ea22c0efc31" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/PostEmploymentBenefitsScheduleofNetPeriodicBenefitCostsDetails" xlink:type="simple" xlink:href="abt-20260930.xsd#PostEmploymentBenefitsScheduleofNetPeriodicBenefitCostsDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/PostEmploymentBenefitsScheduleofNetPeriodicBenefitCostsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_01a043c1-33c7-7eff-9b51-33f78a9c8c04" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit_01a043c1-33c7-7a17-b085-908497713940" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_01a043c1-33c7-7eff-9b51-33f78a9c8c04" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit_01a043c1-33c7-7a17-b085-908497713940" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanInterestCost_01a043c1-33c7-710d-9d22-b7c45136890e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanInterestCost"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_01a043c1-33c7-7eff-9b51-33f78a9c8c04" xlink:to="loc_us-gaap_DefinedBenefitPlanInterestCost_01a043c1-33c7-710d-9d22-b7c45136890e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_01a043c1-33c7-79f0-bd3c-155b2c88ad59" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_01a043c1-33c7-7eff-9b51-33f78a9c8c04" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_01a043c1-33c7-79f0-bd3c-155b2c88ad59" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_01a043c1-33c7-7fb7-bd36-4014ff37d527" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_01a043c1-33c7-7eff-9b51-33f78a9c8c04" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_01a043c1-33c7-7fb7-bd36-4014ff37d527" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanServiceCost_01a043c1-33c7-7332-801e-e852d76faf1b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanServiceCost"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_01a043c1-33c7-7eff-9b51-33f78a9c8c04" xlink:to="loc_us-gaap_DefinedBenefitPlanServiceCost_01a043c1-33c7-7332-801e-e852d76faf1b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/SegmentInformationScheduleofSalesandEarningsDetails" xlink:type="simple" xlink:href="abt-20260930.xsd#SegmentInformationScheduleofSalesandEarningsDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/SegmentInformationScheduleofSalesandEarningsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c7-7a35-bd81-c87437cebe49" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_01a043c1-33c7-7d07-8717-95e030c81f2c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c7-7a35-bd81-c87437cebe49" xlink:to="loc_us-gaap_OperatingIncomeLoss_01a043c1-33c7-7d07-8717-95e030c81f2c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_CorporateAndBenefitPlanCosts_01a043c1-33c7-7abc-9820-236baab96a07" xlink:href="abt-20260930.xsd#abt_CorporateAndBenefitPlanCosts"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c7-7a35-bd81-c87437cebe49" xlink:to="loc_abt_CorporateAndBenefitPlanCosts_01a043c1-33c7-7abc-9820-236baab96a07" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_01a043c1-33c7-73fb-ad74-57d90e98e0ff" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestIncomeExpenseNonoperatingNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c7-7a35-bd81-c87437cebe49" xlink:to="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_01a043c1-33c7-73fb-ad74-57d90e98e0ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_01a043c1-33c7-7664-ac5e-5ec93205974b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c7-7a35-bd81-c87437cebe49" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_01a043c1-33c7-7664-ac5e-5ec93205974b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_01a043c1-33c7-7e98-9710-94b5dc5ec6cf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c7-7a35-bd81-c87437cebe49" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_01a043c1-33c7-7e98-9710-94b5dc5ec6cf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_OtherCostAndExpenseOperatingAndNonoperating_01a043c1-33c7-7488-90c1-22944360c91f" xlink:href="abt-20260930.xsd#abt_OtherCostAndExpenseOperatingAndNonoperating"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a043c1-33c7-7a35-bd81-c87437cebe49" xlink:to="loc_abt_OtherCostAndExpenseOperatingAndNonoperating_01a043c1-33c7-7488-90c1-22944360c91f" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
