<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:343943d3-b7ab-46ab-b623-57bfef5c8f6a,g:2707d60a-391b-438d-854d-dc36e610d3e5-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.abbott.com/role/ConsolidatedStatementofEarnings" xlink:type="simple" xlink:href="abt-20241231.xsd#ConsolidatedStatementofEarnings"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/ConsolidatedStatementofEarnings" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_1aee8784-a5e3-405c-99bd-a78ab3bc79d8" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_490ceb69-0528-47e9-88d2-d4e7897bfa03" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_1aee8784-a5e3-405c-99bd-a78ab3bc79d8" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_490ceb69-0528-47e9-88d2-d4e7897bfa03" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_7d22446e-8e4c-4776-8b8f-6e1fda28c1d2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_1aee8784-a5e3-405c-99bd-a78ab3bc79d8" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_7d22446e-8e4c-4776-8b8f-6e1fda28c1d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_50858902-6388-479a-92f5-de31791a8707" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_42aa0be1-09b2-4b35-b449-f01fcf246d2e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_50858902-6388-479a-92f5-de31791a8707" xlink:to="loc_us-gaap_OperatingIncomeLoss_42aa0be1-09b2-4b35-b449-f01fcf246d2e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseNonoperating_d7d5fa3f-47cd-46ba-90f2-fee0b78b910f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InterestExpenseNonoperating"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_50858902-6388-479a-92f5-de31791a8707" xlink:to="loc_us-gaap_InterestExpenseNonoperating_d7d5fa3f-47cd-46ba-90f2-fee0b78b910f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeInterest_3a01321d-c19a-419e-af7d-490189fa368a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InvestmentIncomeInterest"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_50858902-6388-479a-92f5-de31791a8707" xlink:to="loc_us-gaap_InvestmentIncomeInterest_3a01321d-c19a-419e-af7d-490189fa368a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_31190b54-eb6f-4a65-9002-c5e07783daa0" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_50858902-6388-479a-92f5-de31791a8707" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_31190b54-eb6f-4a65-9002-c5e07783daa0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_d63f5a78-af1c-4a96-98ec-30db4d24c231" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_50858902-6388-479a-92f5-de31791a8707" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_d63f5a78-af1c-4a96-98ec-30db4d24c231" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_f9c56852-2dad-4b49-bb5a-f8d035b1daa6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_ea6c74e7-e359-48d7-8670-79b38d3c8d5d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_f9c56852-2dad-4b49-bb5a-f8d035b1daa6" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_ea6c74e7-e359-48d7-8670-79b38d3c8d5d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_c53fd0d6-848c-479a-9f5a-0c258efb5b93" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CostsAndExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_f9c56852-2dad-4b49-bb5a-f8d035b1daa6" xlink:to="loc_us-gaap_CostsAndExpenses_c53fd0d6-848c-479a-9f5a-0c258efb5b93" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_159c9af0-7e32-49c5-a228-cad9246fb990" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CostsAndExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_085956c1-a4f9-47ac-8348-6323546447d3" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_159c9af0-7e32-49c5-a228-cad9246fb990" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_085956c1-a4f9-47ac-8348-6323546447d3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_3c403212-4ef2-44c3-bba2-ca90d2b77897" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_159c9af0-7e32-49c5-a228-cad9246fb990" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_3c403212-4ef2-44c3-bba2-ca90d2b77897" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_75f09827-f802-4063-bf07-38ca2090a573" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_159c9af0-7e32-49c5-a228-cad9246fb990" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_75f09827-f802-4063-bf07-38ca2090a573" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_51eb2588-f2da-4a74-addb-624f97215286" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_159c9af0-7e32-49c5-a228-cad9246fb990" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_51eb2588-f2da-4a74-addb-624f97215286" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_e2b341e6-13c2-4383-9bd2-cae5c0bcea53" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_33666fc1-4985-4415-88e6-513ef120721f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_e2b341e6-13c2-4383-9bd2-cae5c0bcea53" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_33666fc1-4985-4415-88e6-513ef120721f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_60b760bf-61e0-488b-a8fd-98c055dfc17b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_e2b341e6-13c2-4383-9bd2-cae5c0bcea53" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_60b760bf-61e0-488b-a8fd-98c055dfc17b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/ConsolidatedStatementofComprehensiveIncome" xlink:type="simple" xlink:href="abt-20241231.xsd#ConsolidatedStatementofComprehensiveIncome"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/ConsolidatedStatementofComprehensiveIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_ef6c444c-c044-409c-8c40-158cb2b22762" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_fa3bd24c-28cb-4054-a363-0abe62df9237" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_ef6c444c-c044-409c-8c40-158cb2b22762" xlink:to="loc_us-gaap_NetIncomeLoss_fa3bd24c-28cb-4054-a363-0abe62df9237" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_0173bd69-33e8-4440-bf1c-c993b92eba80" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_ef6c444c-c044-409c-8c40-158cb2b22762" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_0173bd69-33e8-4440-bf1c-c993b92eba80" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_ab8dad54-ebe8-4aa0-9282-ed045c80d41e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax_72b749f7-a265-4bf7-bf1d-ed67bc7022d0" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_ab8dad54-ebe8-4aa0-9282-ed045c80d41e" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossForeignCurrencyTranslationAdjustmentNetOfTax_72b749f7-a265-4bf7-bf1d-ed67bc7022d0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_d5292a65-3afe-4128-b039-0d2df0c72556" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_ab8dad54-ebe8-4aa0-9282-ed045c80d41e" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_d5292a65-3afe-4128-b039-0d2df0c72556" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax_ae7f4a27-05eb-43ca-9b81-087f24d46d02" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_ab8dad54-ebe8-4aa0-9282-ed045c80d41e" xlink:to="loc_us-gaap_AociLossCashFlowHedgeCumulativeGainLossAfterTax_ae7f4a27-05eb-43ca-9b81-087f24d46d02" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_f57549d0-d794-445b-9836-b46b7e19b33a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_2a56ab09-88b1-43d8-919f-5f5a19a3a098" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_f57549d0-d794-445b-9836-b46b7e19b33a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_2a56ab09-88b1-43d8-919f-5f5a19a3a098" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_f880fbce-8e49-4a3f-81a7-96bdb4c45f2e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_f57549d0-d794-445b-9836-b46b7e19b33a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_f880fbce-8e49-4a3f-81a7-96bdb4c45f2e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_d8b71b76-f571-40c2-b6c6-6f2613da080f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_f57549d0-d794-445b-9836-b46b7e19b33a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_d8b71b76-f571-40c2-b6c6-6f2613da080f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/ConsolidatedStatementofCashFlows" xlink:type="simple" xlink:href="abt-20241231.xsd#ConsolidatedStatementofCashFlows"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/ConsolidatedStatementofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_3ae63aaf-1f4f-4c2e-bf3d-176f4af84442" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_437d0a78-dfd6-45e9-a29f-a2753a880bc2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_3ae63aaf-1f4f-4c2e-bf3d-176f4af84442" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_437d0a78-dfd6-45e9-a29f-a2753a880bc2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_PaymentsToAcquireBusinessesNetOfCashAcquiredAndResearchAndDevelopmentInProcess_fd7fb833-0581-4f7f-83f3-7daae8de2ced" xlink:href="abt-20241231.xsd#abt_PaymentsToAcquireBusinessesNetOfCashAcquiredAndResearchAndDevelopmentInProcess"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_3ae63aaf-1f4f-4c2e-bf3d-176f4af84442" xlink:to="loc_abt_PaymentsToAcquireBusinessesNetOfCashAcquiredAndResearchAndDevelopmentInProcess_fd7fb833-0581-4f7f-83f3-7daae8de2ced" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSalesOfBusinessAffiliateAndProductiveAssets_ffc16af7-d1fe-4f57-95cc-a09d51927c83" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ProceedsFromSalesOfBusinessAffiliateAndProductiveAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_3ae63aaf-1f4f-4c2e-bf3d-176f4af84442" xlink:to="loc_us-gaap_ProceedsFromSalesOfBusinessAffiliateAndProductiveAssets_ffc16af7-d1fe-4f57-95cc-a09d51927c83" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireInvestments_c127c708-8ae3-4787-859e-a2b7efbcdd61" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsToAcquireInvestments"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_3ae63aaf-1f4f-4c2e-bf3d-176f4af84442" xlink:to="loc_us-gaap_PaymentsToAcquireInvestments_c127c708-8ae3-4787-859e-a2b7efbcdd61" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfOtherInvestments_41d810d6-da6f-40d6-b793-64f600d9553a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ProceedsFromSaleOfOtherInvestments"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_3ae63aaf-1f4f-4c2e-bf3d-176f4af84442" xlink:to="loc_us-gaap_ProceedsFromSaleOfOtherInvestments_41d810d6-da6f-40d6-b793-64f600d9553a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_00338609-ba56-410b-95a5-dfc1f582d981" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_3ae63aaf-1f4f-4c2e-bf3d-176f4af84442" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_00338609-ba56-410b-95a5-dfc1f582d981" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_00bbd7f1-4507-469d-a693-fe715ada8749" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_8af9a136-b0a4-4e3b-889c-85bc639afb76" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_00bbd7f1-4507-469d-a693-fe715ada8749" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_8af9a136-b0a4-4e3b-889c-85bc639afb76" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_1d176da4-f9ef-4900-8345-21f056c5be11" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_00bbd7f1-4507-469d-a693-fe715ada8749" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_1d176da4-f9ef-4900-8345-21f056c5be11" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_9f88b98a-7190-45de-b1de-eb39d0a20782" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_00bbd7f1-4507-469d-a693-fe715ada8749" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_9f88b98a-7190-45de-b1de-eb39d0a20782" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_a4e71af3-01c5-49c0-97af-bbcc27309dcd" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_00bbd7f1-4507-469d-a693-fe715ada8749" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_a4e71af3-01c5-49c0-97af-bbcc27309dcd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_bbc3d088-5528-4569-b27c-9361b9959499" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebt_9165b410-e41e-482f-ac8b-8c10ea3cec24" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ProceedsFromRepaymentsOfShortTermDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_bbc3d088-5528-4569-b27c-9361b9959499" xlink:to="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebt_9165b410-e41e-482f-ac8b-8c10ea3cec24" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_ProceedsFromLongTermDebtAndDebtMaturingInMoreThanThreeMonths_9d84ed14-692b-4a81-8285-11aa91edda81" xlink:href="abt-20241231.xsd#abt_ProceedsFromLongTermDebtAndDebtMaturingInMoreThanThreeMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_bbc3d088-5528-4569-b27c-9361b9959499" xlink:to="loc_abt_ProceedsFromLongTermDebtAndDebtMaturingInMoreThanThreeMonths_9d84ed14-692b-4a81-8285-11aa91edda81" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_RepaymentsOfLongTermDebtAndDebtMaturingInMoreThanThreeMonths_ef17412d-ca93-42f9-90b2-8361f8ea84d6" xlink:href="abt-20241231.xsd#abt_RepaymentsOfLongTermDebtAndDebtMaturingInMoreThanThreeMonths"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_bbc3d088-5528-4569-b27c-9361b9959499" xlink:to="loc_abt_RepaymentsOfLongTermDebtAndDebtMaturingInMoreThanThreeMonths_ef17412d-ca93-42f9-90b2-8361f8ea84d6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_44afb137-d933-4032-a87d-c3384f8fb527" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_bbc3d088-5528-4569-b27c-9361b9959499" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_44afb137-d933-4032-a87d-c3384f8fb527" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_b7c180da-61c8-4a5f-9fd7-a58343ca1a96" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_bbc3d088-5528-4569-b27c-9361b9959499" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_b7c180da-61c8-4a5f-9fd7-a58343ca1a96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock_b8da2bfe-64d4-42f1-bbba-3c48baf44ef0" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_bbc3d088-5528-4569-b27c-9361b9959499" xlink:to="loc_us-gaap_PaymentsOfDividendsCommonStock_b8da2bfe-64d4-42f1-bbba-3c48baf44ef0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_69d1a78f-77b4-40ab-8141-455db33cd841" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_NetIncomeLoss_69d1a78f-77b4-40ab-8141-455db33cd841" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_fb4682d0-d663-476d-8a62-77829449afcc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Depreciation"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_Depreciation_fb4682d0-d663-476d-8a62-77829449afcc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_af644520-4ea5-456d-9601-d2e60651d720" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_af644520-4ea5-456d-9601-d2e60651d720" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_3dd02733-adac-48ba-89e9-24e9e40e8ab1" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_ShareBasedCompensation_3dd02733-adac-48ba-89e9-24e9e40e8ab1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_InvestingAndFinancingGainsLossesNet_50c22670-5665-489d-9ed3-7fca4c597558" xlink:href="abt-20241231.xsd#abt_InvestingAndFinancingGainsLossesNet"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_abt_InvestingAndFinancingGainsLossesNet_50c22670-5665-489d-9ed3-7fca4c597558" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_db4b14f0-a8ab-4eca-b468-caa0f7239c51" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_db4b14f0-a8ab-4eca-b468-caa0f7239c51" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_2fc460c7-e1c1-4e06-9710-21f4b107cfb7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_2fc460c7-e1c1-4e06-9710-21f4b107cfb7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_4df8d089-b29c-431f-9b81-89223e7e5fb1" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_4df8d089-b29c-431f-9b81-89223e7e5fb1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_474200c6-6e0f-4dde-be39-7a87547ba51a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_474200c6-6e0f-4dde-be39-7a87547ba51a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_73d0e8e4-ae66-4bf8-9927-ac09051faf38" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_34ba99f9-435c-411a-a085-ae49b3812b0c" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_73d0e8e4-ae66-4bf8-9927-ac09051faf38" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/ConsolidatedBalanceSheet" xlink:type="simple" xlink:href="abt-20241231.xsd#ConsolidatedBalanceSheet"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/ConsolidatedBalanceSheet" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_9958657f-03b5-4789-aa18-471b70ecfa00" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_2f3ef35b-c5cf-449e-a017-58e48bc88d22" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_9958657f-03b5-4789-aa18-471b70ecfa00" xlink:to="loc_us-gaap_StockholdersEquity_2f3ef35b-c5cf-449e-a017-58e48bc88d22" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MinorityInterest_1832e98e-c583-4415-b4af-de1ea2e0d325" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_MinorityInterest"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_9958657f-03b5-4789-aa18-471b70ecfa00" xlink:to="loc_us-gaap_MinorityInterest_1832e98e-c583-4415-b4af-de1ea2e0d325" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_98265a4f-57be-4531-8a8c-d657d7b298cb" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_d7301d2e-dee2-4d6c-8f67-1b21ab9dbbde" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_98265a4f-57be-4531-8a8c-d657d7b298cb" xlink:to="loc_us-gaap_AssetsCurrent_d7301d2e-dee2-4d6c-8f67-1b21ab9dbbde" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermInvestments_d76c19de-543b-42ab-a60f-0aeaa3a51bee" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LongTermInvestments"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_98265a4f-57be-4531-8a8c-d657d7b298cb" xlink:to="loc_us-gaap_LongTermInvestments_d76c19de-543b-42ab-a60f-0aeaa3a51bee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_e297b7e8-e17f-46dd-aade-109149ce219d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_98265a4f-57be-4531-8a8c-d657d7b298cb" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_e297b7e8-e17f-46dd-aade-109149ce219d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_becf1591-d3bd-4ba1-9a96-ef8fbee8a564" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_98265a4f-57be-4531-8a8c-d657d7b298cb" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_becf1591-d3bd-4ba1-9a96-ef8fbee8a564" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_f7a96e20-fd70-4311-b635-c4b836d02bfd" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_98265a4f-57be-4531-8a8c-d657d7b298cb" xlink:to="loc_us-gaap_Goodwill_f7a96e20-fd70-4311-b635-c4b836d02bfd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndOtherAssetsNoncurrent_dc349c67-b1f9-4efd-9c63-7d43bbaaaa6a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredIncomeTaxesAndOtherAssetsNoncurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_98265a4f-57be-4531-8a8c-d657d7b298cb" xlink:to="loc_us-gaap_DeferredIncomeTaxesAndOtherAssetsNoncurrent_dc349c67-b1f9-4efd-9c63-7d43bbaaaa6a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_28e375be-334d-4d18-87b2-21e12326fcf4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_5a878038-9ec5-4fb3-9c30-448224b3508d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PreferredStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_28e375be-334d-4d18-87b2-21e12326fcf4" xlink:to="loc_us-gaap_PreferredStockValue_5a878038-9ec5-4fb3-9c30-448224b3508d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_cbe33b66-0837-4947-a098-49f347d3f26a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_28e375be-334d-4d18-87b2-21e12326fcf4" xlink:to="loc_us-gaap_CommonStockValue_cbe33b66-0837-4947-a098-49f347d3f26a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonValue_75ba128d-6eaa-4313-b2d5-e1a44a3037a4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_TreasuryStockCommonValue"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_28e375be-334d-4d18-87b2-21e12326fcf4" xlink:to="loc_us-gaap_TreasuryStockCommonValue_75ba128d-6eaa-4313-b2d5-e1a44a3037a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_f3869013-6f21-4403-a00d-22f312511257" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_28e375be-334d-4d18-87b2-21e12326fcf4" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_f3869013-6f21-4403-a00d-22f312511257" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_8d082899-d34d-448d-9461-3a22f45c7e52" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_28e375be-334d-4d18-87b2-21e12326fcf4" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_8d082899-d34d-448d-9461-3a22f45c7e52" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_df3ce02a-e01c-4525-8d11-3ebbd673efe4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Land_ae411877-5b3b-4b2f-b183-f5e24beb1836" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Land"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_df3ce02a-e01c-4525-8d11-3ebbd673efe4" xlink:to="loc_us-gaap_Land_ae411877-5b3b-4b2f-b183-f5e24beb1836" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BuildingsAndImprovementsGross_7c969d6c-bc7e-4384-882b-efa72d0f0af2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_BuildingsAndImprovementsGross"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_df3ce02a-e01c-4525-8d11-3ebbd673efe4" xlink:to="loc_us-gaap_BuildingsAndImprovementsGross_7c969d6c-bc7e-4384-882b-efa72d0f0af2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MachineryAndEquipmentGross_891da199-e9b6-477a-b9c8-982cf7f08121" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_MachineryAndEquipmentGross"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_df3ce02a-e01c-4525-8d11-3ebbd673efe4" xlink:to="loc_us-gaap_MachineryAndEquipmentGross_891da199-e9b6-477a-b9c8-982cf7f08121" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConstructionInProgressGross_524ca80f-7fa8-4552-bc6b-586376d0a957" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ConstructionInProgressGross"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_df3ce02a-e01c-4525-8d11-3ebbd673efe4" xlink:to="loc_us-gaap_ConstructionInProgressGross_524ca80f-7fa8-4552-bc6b-586376d0a957" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_cca590fe-c943-427c-b8ce-855293ebc538" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableTradeCurrent_2f5bcf55-4bd1-40a7-a833-301020a86543" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccountsPayableTradeCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_cca590fe-c943-427c-b8ce-855293ebc538" xlink:to="loc_us-gaap_AccountsPayableTradeCurrent_2f5bcf55-4bd1-40a7-a833-301020a86543" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_cfa561de-c4c6-4bde-a8b0-cb8fda97f9e7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_cca590fe-c943-427c-b8ce-855293ebc538" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_cfa561de-c4c6-4bde-a8b0-cb8fda97f9e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_b269fe9c-6aee-4542-bb0b-f6bb927c090e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_cca590fe-c943-427c-b8ce-855293ebc538" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_b269fe9c-6aee-4542-bb0b-f6bb927c090e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsPayableCurrent_1cc3f04b-f648-4711-98f6-983bd05abbfc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DividendsPayableCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_cca590fe-c943-427c-b8ce-855293ebc538" xlink:to="loc_us-gaap_DividendsPayableCurrent_1cc3f04b-f648-4711-98f6-983bd05abbfc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedIncomeTaxesCurrent_4f65e5db-d9e7-48fa-8a27-c33f2c07afc6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccruedIncomeTaxesCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_cca590fe-c943-427c-b8ce-855293ebc538" xlink:to="loc_us-gaap_AccruedIncomeTaxesCurrent_4f65e5db-d9e7-48fa-8a27-c33f2c07afc6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_2449d3ea-8ea6-407c-b955-54e2484be194" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_cca590fe-c943-427c-b8ce-855293ebc538" xlink:to="loc_us-gaap_LongTermDebtCurrent_2449d3ea-8ea6-407c-b955-54e2484be194" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_35d46476-73eb-4e7c-afff-cb2d577ee3c3" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InventoryNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_6736d618-7302-4703-9503-27c0efe6ef5f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_35d46476-73eb-4e7c-afff-cb2d577ee3c3" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_6736d618-7302-4703-9503-27c0efe6ef5f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_7ae0271c-37a3-4a99-b58b-503df62b8a70" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_35d46476-73eb-4e7c-afff-cb2d577ee3c3" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_7ae0271c-37a3-4a99-b58b-503df62b8a70" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_f56e5248-1ede-4da6-8e62-9dfb0794db2c" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InventoryRawMaterialsNetOfReserves"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_35d46476-73eb-4e7c-afff-cb2d577ee3c3" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_f56e5248-1ede-4da6-8e62-9dfb0794db2c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_e914c585-6dbb-4ba6-99d5-d47e567fc4c9" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_247e433b-b208-44dd-a982-955dd69d3704" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_e914c585-6dbb-4ba6-99d5-d47e567fc4c9" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_247e433b-b208-44dd-a982-955dd69d3704" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermInvestments_9408ff26-c6ab-4752-afc4-8ce1c3499585" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ShortTermInvestments"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_e914c585-6dbb-4ba6-99d5-d47e567fc4c9" xlink:to="loc_us-gaap_ShortTermInvestments_9408ff26-c6ab-4752-afc4-8ce1c3499585" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_93d11c1d-c898-43d8-905d-1b4c73a99ed7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_e914c585-6dbb-4ba6-99d5-d47e567fc4c9" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_93d11c1d-c898-43d8-905d-1b4c73a99ed7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_9620bbf7-0e70-4bad-a815-12612ad3e6f4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InventoryNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_e914c585-6dbb-4ba6-99d5-d47e567fc4c9" xlink:to="loc_us-gaap_InventoryNet_9620bbf7-0e70-4bad-a815-12612ad3e6f4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_PrepaidExpenseAndOtherReceivables_222f22b9-48ad-4dae-b67e-0999f09b92e6" xlink:href="abt-20241231.xsd#abt_PrepaidExpenseAndOtherReceivables"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_e914c585-6dbb-4ba6-99d5-d47e567fc4c9" xlink:to="loc_abt_PrepaidExpenseAndOtherReceivables_222f22b9-48ad-4dae-b67e-0999f09b92e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_7d339606-c72f-4d5c-8496-c54bb24c6aff" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_665e0d15-2165-48f3-8d06-004303ed4160" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_7d339606-c72f-4d5c-8496-c54bb24c6aff" xlink:to="loc_us-gaap_LiabilitiesCurrent_665e0d15-2165-48f3-8d06-004303ed4160" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_709c5eb5-5ac1-4ea3-be80-35d0b150efdd" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_7d339606-c72f-4d5c-8496-c54bb24c6aff" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_709c5eb5-5ac1-4ea3-be80-35d0b150efdd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_dacecd0f-3b2b-4de1-b1df-2cff98b41262" xlink:href="abt-20241231.xsd#abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_7d339606-c72f-4d5c-8496-c54bb24c6aff" xlink:to="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_dacecd0f-3b2b-4de1-b1df-2cff98b41262" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_4dfcc991-769d-4d6d-904e-a464bb8aa105" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_7d339606-c72f-4d5c-8496-c54bb24c6aff" xlink:to="loc_us-gaap_CommitmentsAndContingencies_4dfcc991-769d-4d6d-904e-a464bb8aa105" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_a8ba5e9d-c6ae-4518-a16f-410bcb5d9ecf" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_7d339606-c72f-4d5c-8496-c54bb24c6aff" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_a8ba5e9d-c6ae-4518-a16f-410bcb5d9ecf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_3a783ad9-c7c8-4cec-b914-beae6e6e0b69" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_2d79cdfc-2a87-4173-ac59-c16f2bbac009" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_3a783ad9-c7c8-4cec-b914-beae6e6e0b69" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_2d79cdfc-2a87-4173-ac59-c16f2bbac009" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_1bfdd438-edcd-4ad5-98ca-954b15f1b3f0" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_3a783ad9-c7c8-4cec-b914-beae6e6e0b69" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_1bfdd438-edcd-4ad5-98ca-954b15f1b3f0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/SupplementalFinancialInformationOtherAccruedLiabilitiesDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#SupplementalFinancialInformationOtherAccruedLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/SupplementalFinancialInformationOtherAccruedLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_2cf6138d-45cb-4739-a518-44167fa810c5" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_AccruedRebatesPayableToGovernmentAgencies_4ffd9c84-7f1a-4051-9edf-10be8b3471ec" xlink:href="abt-20241231.xsd#abt_AccruedRebatesPayableToGovernmentAgencies"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAccruedLiabilitiesCurrent_2cf6138d-45cb-4739-a518-44167fa810c5" xlink:to="loc_abt_AccruedRebatesPayableToGovernmentAgencies_4ffd9c84-7f1a-4051-9edf-10be8b3471ec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_AccruedOtherRebates_f49d905d-b873-49df-9e3b-28e77ab8a0cc" xlink:href="abt-20241231.xsd#abt_AccruedOtherRebates"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAccruedLiabilitiesCurrent_2cf6138d-45cb-4739-a518-44167fa810c5" xlink:to="loc_abt_AccruedOtherRebates_f49d905d-b873-49df-9e3b-28e77ab8a0cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_AllOtherAccruedLiabilities_12944a8e-afd2-48d2-a013-0b833bbfc90b" xlink:href="abt-20241231.xsd#abt_AllOtherAccruedLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAccruedLiabilitiesCurrent_2cf6138d-45cb-4739-a518-44167fa810c5" xlink:to="loc_abt_AllOtherAccruedLiabilities_12944a8e-afd2-48d2-a013-0b833bbfc90b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/SupplementalFinancialInformationPostemploymentObligationsandOtherLongtermLiabilitiesDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#SupplementalFinancialInformationPostemploymentObligationsandOtherLongtermLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/SupplementalFinancialInformationPostemploymentObligationsandOtherLongtermLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_da42746d-ba70-4f4c-97af-42d5e0e510d0" xlink:href="abt-20241231.xsd#abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent_3af43dd5-7448-474b-aed2-7f85f421ba7a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_da42746d-ba70-4f4c-97af-42d5e0e510d0" xlink:to="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent_3af43dd5-7448-474b-aed2-7f85f421ba7a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_AggregateDeferredTaxLiabilitiesNetOfAssetsAndNetOfValuationAllowanceNoncurrent_a2543255-66b8-4017-952b-58d30c3b2fbc" xlink:href="abt-20241231.xsd#abt_AggregateDeferredTaxLiabilitiesNetOfAssetsAndNetOfValuationAllowanceNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_da42746d-ba70-4f4c-97af-42d5e0e510d0" xlink:to="loc_abt_AggregateDeferredTaxLiabilitiesNetOfAssetsAndNetOfValuationAllowanceNoncurrent_a2543255-66b8-4017-952b-58d30c3b2fbc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_2410b9d5-0920-4113-bbdf-7a8bff5b5693" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_da42746d-ba70-4f4c-97af-42d5e0e510d0" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_2410b9d5-0920-4113-bbdf-7a8bff5b5693" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_4bf05488-e144-4653-835b-dc9d4ac157bb" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_abt_PostEmploymentObligationsDeferredIncomeTaxesAndOtherLongTermLiabilities_da42746d-ba70-4f4c-97af-42d5e0e510d0" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_4bf05488-e144-4653-835b-dc9d4ac157bb" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/AccumulatedOtherComprehensiveIncomeLossDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#AccumulatedOtherComprehensiveIncomeLossDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/AccumulatedOtherComprehensiveIncomeLossDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_0920d133-01b0-4a93-91a4-770db0f4f307" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_01bf798f-9832-47f7-a385-8d8cf2370034" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_0920d133-01b0-4a93-91a4-770db0f4f307" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_01bf798f-9832-47f7-a385-8d8cf2370034" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_be734127-0245-45da-92c2-663827091f23" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_0920d133-01b0-4a93-91a4-770db0f4f307" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_be734127-0245-45da-92c2-663827091f23" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/DebtandLinesofCreditSummaryofLongtermDebtDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#DebtandLinesofCreditSummaryofLongtermDebtDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/DebtandLinesofCreditSummaryofLongtermDebtDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_2ae7ac24-97d9-4965-8f87-f8e5f16d49d8" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_72781153-6b02-4b7d-8889-dd5acc529fb2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_2ae7ac24-97d9-4965-8f87-f8e5f16d49d8" xlink:to="loc_us-gaap_LongTermDebtCurrent_72781153-6b02-4b7d-8889-dd5acc529fb2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_1247019f-4fe0-40c8-880d-75409efd9942" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_2ae7ac24-97d9-4965-8f87-f8e5f16d49d8" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_1247019f-4fe0-40c8-880d-75409efd9942" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/DebtandLinesofCreditSummaryofLongtermDebtDetails_1" xlink:type="simple" xlink:href="abt-20241231.xsd#DebtandLinesofCreditSummaryofLongtermDebtDetails_1"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/DebtandLinesofCreditSummaryofLongtermDebtDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_c2c504f4-6665-48df-947a-24f1ac23c8fa" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_e4eff7ee-95bd-4011-9f65-05d7bd9388fb" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_c2c504f4-6665-48df-947a-24f1ac23c8fa" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_e4eff7ee-95bd-4011-9f65-05d7bd9388fb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnamortizedDebtIssuanceExpense_90aa52ec-2b6b-4912-9a74-90ee2d85c056" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_UnamortizedDebtIssuanceExpense"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_c2c504f4-6665-48df-947a-24f1ac23c8fa" xlink:to="loc_us-gaap_UnamortizedDebtIssuanceExpense_90aa52ec-2b6b-4912-9a74-90ee2d85c056" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_LongTermDebtOther_c4d06fda-0e37-4d5f-bbd7-d134d388c459" xlink:href="abt-20241231.xsd#abt_LongTermDebtOther"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_c2c504f4-6665-48df-947a-24f1ac23c8fa" xlink:to="loc_abt_LongTermDebtOther_c4d06fda-0e37-4d5f-bbd7-d134d388c459" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/LeasesFutureMinimumLeasePaymentsDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#LeasesFutureMinimumLeasePaymentsDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/LeasesFutureMinimumLeasePaymentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_db91291b-316e-4ec8-8d7b-4d6ea2d0e0e3" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_533ca97d-b5e5-433f-9b01-96a422cf0d6c" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_db91291b-316e-4ec8-8d7b-4d6ea2d0e0e3" xlink:to="loc_us-gaap_OperatingLeaseLiability_533ca97d-b5e5-433f-9b01-96a422cf0d6c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_a65140d6-da3f-48bb-8f73-3229a5e197cf" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_db91291b-316e-4ec8-8d7b-4d6ea2d0e0e3" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_a65140d6-da3f-48bb-8f73-3229a5e197cf" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/LeasesFutureMinimumLeasePaymentsDetails_1" xlink:type="simple" xlink:href="abt-20241231.xsd#LeasesFutureMinimumLeasePaymentsDetails_1"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/LeasesFutureMinimumLeasePaymentsDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_3bed7d98-54d8-4510-bc53-0594641713ed" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_242981ae-c9a6-455c-9ee8-ebcfd48e6b17" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_3bed7d98-54d8-4510-bc53-0594641713ed" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_242981ae-c9a6-455c-9ee8-ebcfd48e6b17" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_d6927df4-32c4-4dad-a08b-fc34410bf6d1" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_3bed7d98-54d8-4510-bc53-0594641713ed" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_d6927df4-32c4-4dad-a08b-fc34410bf6d1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_31ed523e-74b2-47c1-b174-c84d1fef9b5a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_3bed7d98-54d8-4510-bc53-0594641713ed" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_31ed523e-74b2-47c1-b174-c84d1fef9b5a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_ec68aa07-7256-4e7b-b139-802ec84c2890" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_3bed7d98-54d8-4510-bc53-0594641713ed" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_ec68aa07-7256-4e7b-b139-802ec84c2890" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_6abf65d6-e619-458d-9cd7-54d3d7740ef6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_3bed7d98-54d8-4510-bc53-0594641713ed" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_6abf65d6-e619-458d-9cd7-54d3d7740ef6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_a0252ddf-e9c1-4763-9d99-0658b322f2d8" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_3bed7d98-54d8-4510-bc53-0594641713ed" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_a0252ddf-e9c1-4763-9d99-0658b322f2d8" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/LeasesROUAssetsandLeaseLiabilitiesDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#LeasesROUAssetsandLeaseLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/LeasesROUAssetsandLeaseLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_24724fb7-2d99-404b-a831-2f0743c1da27" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_90edb70b-2ec0-489a-a051-9b93c0d65f22" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeaseLiability_24724fb7-2d99-404b-a831-2f0743c1da27" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_90edb70b-2ec0-489a-a051-9b93c0d65f22" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_80830da2-1492-4b8a-a4af-3cba0dc6c945" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeaseLiability_24724fb7-2d99-404b-a831-2f0743c1da27" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_80830da2-1492-4b8a-a4af-3cba0dc6c945" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/FinancialInstrumentsDerivativesandFairValueMeasuresBasesofMeasurementDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#FinancialInstrumentsDerivativesandFairValueMeasuresBasesofMeasurementDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/FinancialInstrumentsDerivativesandFairValueMeasuresBasesofMeasurementDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_54bc5fca-f2fb-40a0-bca3-563f7661faf7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgedLiabilityFairValueHedge_04a4189f-d505-4344-8222-278bd5dc14d2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_HedgedLiabilityFairValueHedge"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_54bc5fca-f2fb-40a0-bca3-563f7661faf7" xlink:to="loc_us-gaap_HedgedLiabilityFairValueHedge_04a4189f-d505-4344-8222-278bd5dc14d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateDerivativeLiabilitiesAtFairValue_6940ec66-fa6d-4145-94b0-675f2e973344" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InterestRateDerivativeLiabilitiesAtFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_54bc5fca-f2fb-40a0-bca3-563f7661faf7" xlink:to="loc_us-gaap_InterestRateDerivativeLiabilitiesAtFairValue_6940ec66-fa6d-4145-94b0-675f2e973344" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue_6ae71141-1e4e-4729-8a7f-a357e56bddf5" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_54bc5fca-f2fb-40a0-bca3-563f7661faf7" xlink:to="loc_us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue_6ae71141-1e4e-4729-8a7f-a357e56bddf5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_fbea0745-6233-4afd-b4bc-770b49da59fb" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_54bc5fca-f2fb-40a0-bca3-563f7661faf7" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_fbea0745-6233-4afd-b4bc-770b49da59fb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_0bfc190b-b24e-4c01-b53b-050b9976bb2d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_85bea398-27b8-4eb9-b811-388b0597acc9" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_0bfc190b-b24e-4c01-b53b-050b9976bb2d" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_85bea398-27b8-4eb9-b811-388b0597acc9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyCashFlowHedgeAssetAtFairValue_f68d7a43-66d4-4617-b52a-e47a93d393f8" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ForeignCurrencyCashFlowHedgeAssetAtFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_0bfc190b-b24e-4c01-b53b-050b9976bb2d" xlink:to="loc_us-gaap_ForeignCurrencyCashFlowHedgeAssetAtFairValue_f68d7a43-66d4-4617-b52a-e47a93d393f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateDerivativeAssetsAtFairValue_1a79a927-18e3-46ae-a344-a07c325cc256" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InterestRateDerivativeAssetsAtFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_0bfc190b-b24e-4c01-b53b-050b9976bb2d" xlink:to="loc_us-gaap_InterestRateDerivativeAssetsAtFairValue_1a79a927-18e3-46ae-a344-a07c325cc256" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/PostEmploymentBenefitsSummaryofBenefitPlansDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#PostEmploymentBenefitsSummaryofBenefitPlansDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/PostEmploymentBenefitsSummaryofBenefitPlansDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet_3ac46cc9-24f9-4fdf-ae30-3c4a081b29ed" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent_90d84c31-4905-4ebd-80f1-64691126ca80" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet_3ac46cc9-24f9-4fdf-ae30-3c4a081b29ed" xlink:to="loc_us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent_90d84c31-4905-4ebd-80f1-64691126ca80" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansCurrentLiabilities_d431edd9-0e23-4bd6-a9b3-61d4851e31db" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansCurrentLiabilities"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet_3ac46cc9-24f9-4fdf-ae30-3c4a081b29ed" xlink:to="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansCurrentLiabilities_d431edd9-0e23-4bd6-a9b3-61d4851e31db" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent_448dbcc1-e641-40f0-9414-bacd0ba27bfb" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanAmountsRecognizedInBalanceSheet_3ac46cc9-24f9-4fdf-ae30-3c4a081b29ed" xlink:to="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent_448dbcc1-e641-40f0-9414-bacd0ba27bfb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTax_2053daff-b0cb-4baa-b062-e643d5a07131" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesBeforeTax_ad6ac969-a9bb-4a4e-ad64-36a76f1631cf" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTax_2053daff-b0cb-4baa-b062-e643d5a07131" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetGainsLossesBeforeTax_ad6ac969-a9bb-4a4e-ad64-36a76f1631cf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditBeforeTax_044dd0cf-a8f5-42a2-a73e-e82d1e2244a1" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeBeforeTax_2053daff-b0cb-4baa-b062-e643d5a07131" xlink:to="loc_us-gaap_DefinedBenefitPlanAccumulatedOtherComprehensiveIncomeNetPriorServiceCostCreditBeforeTax_044dd0cf-a8f5-42a2-a73e-e82d1e2244a1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFundedStatusOfPlan_e89d95f3-ab7f-4f2e-9096-e79454589a9b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanFundedStatusOfPlan"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligation_97a77db1-b7c4-4eb7-8600-761694fe6030" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanBenefitObligation"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanFundedStatusOfPlan_e89d95f3-ab7f-4f2e-9096-e79454589a9b" xlink:to="loc_us-gaap_DefinedBenefitPlanBenefitObligation_97a77db1-b7c4-4eb7-8600-761694fe6030" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_944597d5-5848-4f5e-b821-e098e06feac4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanFundedStatusOfPlan_e89d95f3-ab7f-4f2e-9096-e79454589a9b" xlink:to="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_944597d5-5848-4f5e-b821-e098e06feac4" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/PostEmploymentBenefitsNetPeriodicBenefitCostDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#PostEmploymentBenefitsNetPeriodicBenefitCostDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/PostEmploymentBenefitsNetPeriodicBenefitCostDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_11c2311b-e76c-4a9f-98a5-4c0c818eb812" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanServiceCost_bccd4fef-42ce-40b4-af90-9d6f412e529f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanServiceCost"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_11c2311b-e76c-4a9f-98a5-4c0c818eb812" xlink:to="loc_us-gaap_DefinedBenefitPlanServiceCost_bccd4fef-42ce-40b4-af90-9d6f412e529f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanInterestCost_6bbad62a-7f0b-424b-8f83-2a3c7aa26a87" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanInterestCost"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_11c2311b-e76c-4a9f-98a5-4c0c818eb812" xlink:to="loc_us-gaap_DefinedBenefitPlanInterestCost_6bbad62a-7f0b-424b-8f83-2a3c7aa26a87" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_31591ed7-1db8-438e-8806-355e74b5d43d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_11c2311b-e76c-4a9f-98a5-4c0c818eb812" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_31591ed7-1db8-438e-8806-355e74b5d43d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_a404063e-1772-4089-a56a-f8f3afec60a7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_11c2311b-e76c-4a9f-98a5-4c0c818eb812" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_a404063e-1772-4089-a56a-f8f3afec60a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit_a6cb337d-7a13-4a10-8309-8483a6d4b248" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_11c2311b-e76c-4a9f-98a5-4c0c818eb812" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfPriorServiceCostCredit_a6cb337d-7a13-4a10-8309-8483a6d4b248" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/TaxesonEarningsEarningsandTaxesDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#TaxesonEarningsEarningsandTaxesDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/TaxesonEarningsEarningsandTaxesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_a06820be-9f31-448f-9140-81344113da52" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFederalStateAndLocalTaxExpenseBenefit_45680aeb-bf47-4615-aa8a-1d5b961ddc37" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredFederalStateAndLocalTaxExpenseBenefit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_a06820be-9f31-448f-9140-81344113da52" xlink:to="loc_us-gaap_DeferredFederalStateAndLocalTaxExpenseBenefit_45680aeb-bf47-4615-aa8a-1d5b961ddc37" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_3094c850-7ac0-4566-a180-759d67909c79" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredForeignIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_a06820be-9f31-448f-9140-81344113da52" xlink:to="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_3094c850-7ac0-4566-a180-759d67909c79" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_68c9c038-97d6-4716-99ed-44cbfa83c347" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_a9d8c45d-037f-45d0-8f09-a4019ffb6d5e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_68c9c038-97d6-4716-99ed-44cbfa83c347" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_a9d8c45d-037f-45d0-8f09-a4019ffb6d5e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_325b0509-f4f8-4e05-aba3-25a775e009fe" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_68c9c038-97d6-4716-99ed-44cbfa83c347" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_325b0509-f4f8-4e05-aba3-25a775e009fe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_83200c44-11b5-4cb0-8689-7ca9b9801afc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_6a742af7-60df-45a9-a717-db8fc2d56239" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_83200c44-11b5-4cb0-8689-7ca9b9801afc" xlink:to="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_6a742af7-60df-45a9-a717-db8fc2d56239" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_b10187cf-f66b-4485-812d-8c75a85bcbee" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_83200c44-11b5-4cb0-8689-7ca9b9801afc" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_b10187cf-f66b-4485-812d-8c75a85bcbee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_e7312492-a1e1-49c9-ad45-ae7ed120b6f4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentFederalStateAndLocalTaxExpenseBenefit_74cf0fa9-3319-4d25-99f9-5c2c9fd3ae3a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CurrentFederalStateAndLocalTaxExpenseBenefit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_e7312492-a1e1-49c9-ad45-ae7ed120b6f4" xlink:to="loc_us-gaap_CurrentFederalStateAndLocalTaxExpenseBenefit_74cf0fa9-3319-4d25-99f9-5c2c9fd3ae3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentForeignTaxExpenseBenefit_3f852183-5149-4d1a-ba88-99fc66263a14" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CurrentForeignTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_e7312492-a1e1-49c9-ad45-ae7ed120b6f4" xlink:to="loc_us-gaap_CurrentForeignTaxExpenseBenefit_3f852183-5149-4d1a-ba88-99fc66263a14" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/TaxesonEarningsTaxRateReconciliationDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#TaxesonEarningsTaxRateReconciliationDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/TaxesonEarningsTaxRateReconciliationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch_11b05729-2d00-4ee3-b501-7c1b0e545de4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch_11b05729-2d00-4ee3-b501-7c1b0e545de4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_dde4d0ea-f1ba-455f-ae61-5ca3fafeb069" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_dde4d0ea-f1ba-455f-ae61-5ca3fafeb069" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost_351cf3c0-9a1e-47d9-b7b4-53ab82952b8b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost_351cf3c0-9a1e-47d9-b7b4-53ab82952b8b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_80d4c053-6654-4e92-a982-fdf4326ac124" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_80d4c053-6654-4e92-a982-fdf4326ac124" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_d0fbf994-d223-4d6a-9ffc-ce79a40b1316" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_d0fbf994-d223-4d6a-9ffc-ce79a40b1316" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes_92c00a4e-3e3c-42f5-b340-ed247ca7f2c8" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes_92c00a4e-3e3c-42f5-b340-ed247ca7f2c8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_EffectiveIncomeTaxReconciliationIntercompanyRestructuringsAndIntegrationPercent_cff265d8-5084-438f-8d99-887d0d4f08c8" xlink:href="abt-20241231.xsd#abt_EffectiveIncomeTaxReconciliationIntercompanyRestructuringsAndIntegrationPercent"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_abt_EffectiveIncomeTaxReconciliationIntercompanyRestructuringsAndIntegrationPercent_cff265d8-5084-438f-8d99-887d0d4f08c8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationFdiiPercent_91a7d3eb-bb74-4d31-b574-7b6014464e50" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationFdiiPercent"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationFdiiPercent_91a7d3eb-bb74-4d31-b574-7b6014464e50" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments_fcb1c953-d9ed-43a8-b3d6-e19163802e77" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments_fcb1c953-d9ed-43a8-b3d6-e19163802e77" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_13750e34-f2a8-42af-96f9-214c4d27ba8f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_93e1f9f4-053f-49b5-9c59-eedc93c7ed4c" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_13750e34-f2a8-42af-96f9-214c4d27ba8f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.abbott.com/role/TaxesonEarningsDeferredTaxAssetsandLiabilitiesDetails" xlink:type="simple" xlink:href="abt-20241231.xsd#TaxesonEarningsDeferredTaxAssetsandLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.abbott.com/role/TaxesonEarningsDeferredTaxAssetsandLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_011ac181-447e-4a00-987b-8e6a19d7a2bc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_64ec74bd-feca-4372-a4e2-ad2738b4f21b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_011ac181-447e-4a00-987b-8e6a19d7a2bc" xlink:to="loc_us-gaap_DeferredTaxAssetsGross_64ec74bd-feca-4372-a4e2-ad2738b4f21b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_32b912e6-4fb0-4911-91bb-1d9bfdc734bb" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_011ac181-447e-4a00-987b-8e6a19d7a2bc" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_32b912e6-4fb0-4911-91bb-1d9bfdc734bb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_7ac552c5-6cb1-44b6-873e-4ef983e147ca" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_330e0bb2-b920-4be6-bb09-958952e05167" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredIncomeTaxLiabilities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_7ac552c5-6cb1-44b6-873e-4ef983e147ca" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilities_330e0bb2-b920-4be6-bb09-958952e05167" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_ae520093-ef84-47f7-9602-823bdc039339" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_7ac552c5-6cb1-44b6-873e-4ef983e147ca" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_ae520093-ef84-47f7-9602-823bdc039339" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_4f2bcded-c1ed-4b61-97ef-11f4a53b2b2d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsGross"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits_f4e8d734-996e-4ae5-bfae-1ff4d1f631f0" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_4f2bcded-c1ed-4b61-97ef-11f4a53b2b2d" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits_f4e8d734-996e-4ae5-bfae-1ff4d1f631f0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_020890dc-f982-4d82-99e9-8cc4c50aeab8" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_4f2bcded-c1ed-4b61-97ef-11f4a53b2b2d" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_020890dc-f982-4d82-99e9-8cc4c50aeab8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment_388e54d5-1271-4bb3-b696-ce217d54cfd9" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_4f2bcded-c1ed-4b61-97ef-11f4a53b2b2d" xlink:to="loc_us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment_388e54d5-1271-4bb3-b696-ce217d54cfd9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsInventory_655295f5-e838-46bd-afe0-e36dc87ed5ad" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsInventory"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_4f2bcded-c1ed-4b61-97ef-11f4a53b2b2d" xlink:to="loc_us-gaap_DeferredTaxAssetsInventory_655295f5-e838-46bd-afe0-e36dc87ed5ad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_DeferredTaxAssetsLeaseLiabilities_ca8232b8-1f66-497a-bca2-a669375f63f3" xlink:href="abt-20241231.xsd#abt_DeferredTaxAssetsLeaseLiabilities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_4f2bcded-c1ed-4b61-97ef-11f4a53b2b2d" xlink:to="loc_abt_DeferredTaxAssetsLeaseLiabilities_ca8232b8-1f66-497a-bca2-a669375f63f3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_DeferredTaxAssetsIntercompanyProfit_f7f406c7-8f6c-4f2a-adaf-602cc0f2cfcd" xlink:href="abt-20241231.xsd#abt_DeferredTaxAssetsIntercompanyProfit"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_4f2bcded-c1ed-4b61-97ef-11f4a53b2b2d" xlink:to="loc_abt_DeferredTaxAssetsIntercompanyProfit_f7f406c7-8f6c-4f2a-adaf-602cc0f2cfcd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOther_0198fe2f-cdae-4f64-a754-570c71a59b70" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxAssetsOther"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_4f2bcded-c1ed-4b61-97ef-11f4a53b2b2d" xlink:to="loc_us-gaap_DeferredTaxAssetsOther_0198fe2f-cdae-4f64-a754-570c71a59b70" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_62a97381-772b-418a-96cc-306bf91e6edc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredIncomeTaxLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_f76180ca-62a8-4e2c-a689-7642ca5bab0b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_62a97381-772b-418a-96cc-306bf91e6edc" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_f76180ca-62a8-4e2c-a689-7642ca5bab0b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_DeferredTaxLiabilitiesCompensationAndBenefits_0511263c-7610-4809-b064-82d99df4b9f8" xlink:href="abt-20241231.xsd#abt_DeferredTaxLiabilitiesCompensationAndBenefits"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_62a97381-772b-418a-96cc-306bf91e6edc" xlink:to="loc_abt_DeferredTaxLiabilitiesCompensationAndBenefits_0511263c-7610-4809-b064-82d99df4b9f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesOther_a5085c10-af09-4a5a-9a26-9c3d7295af91" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredTaxLiabilitiesOther"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_62a97381-772b-418a-96cc-306bf91e6edc" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesOther_a5085c10-af09-4a5a-9a26-9c3d7295af91" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_abt_DeferredTaxLiabilitiesRightOfUseLeaseAssets_41a5ad9c-3858-4c5a-8965-125e8ba51b81" xlink:href="abt-20241231.xsd#abt_DeferredTaxLiabilitiesRightOfUseLeaseAssets"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_62a97381-772b-418a-96cc-306bf91e6edc" xlink:to="loc_abt_DeferredTaxLiabilitiesRightOfUseLeaseAssets_41a5ad9c-3858-4c5a-8965-125e8ba51b81" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
